Files and links (1)
Accepted (AM)Open Access (License Unspecified), Open
Journal article
Social position and chronic conditions across the life span and risk of stroke: a life course epidemiological analysis of 22 847 American adults in ages over 50
International journal of stroke, v 8(SA100), pp 50-61
01 Oct 2013
PMID: 23231424
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background Evidence is limited on the impact of childhood socioeconomic status, adulthood socioeconomic status and chronic conditions on risk of incident stroke in later life. We aimed to examine these associations using data from a nationally representative sample of the Health and Retirement Study.
Methods Stroke-free participants (n=22847) aged>50 years in the Health and Retirement Study (1992-2008) were analyzed. Childhood and adulthood socioeconomic status were assessed using parental and participant's education attainments. Incident stroke was defined as self-reported first incident stroke.
Results Of the study sample, 2298 subjects experienced first incident stroke (1006%). Cox's regression models indicate that subjects with low childhood socioeconomic status had 136 times higher risk (95% confidence interval: 118-157) of first incident stroke than those with high childhood socioeconomic status. There was an 8% reduction of this association after adjustment for adulthood socioeconomic status. Adults with diabetes mellitus had the highest hazard ratio (191, 95% confidence interval: 163-223) for incident stroke, followed by heart disease (169, 148-193), and then hypertension (156, 140-175). Significant interaction effect of childhood socioeconomic status and diabetes mellitus, and combined effects of socioeconomic status and chronic conditions on risk of incident stroke were observed.
Conclusions Both low socioeconomic status in childhood and adulthood socioeconomic status predict the risk of stroke. There are significantly combined effects of socioeconomic status and chronic conditions on the risk of stroke. Improving socioeconomic status across the life span and aggressive control of chronic conditions may play pivotal roles in the prevention of stroke development.
Metrics
Details
- Title
- Social position and chronic conditions across the life span and risk of stroke: a life course epidemiological analysis of 22 847 American adults in ages over 50
- Creators
- Longjian Liu - Drexel UniversityFuzhong Xue - Shandong UniversityJixiang Ma - National Center for Chronic and Noncommunicable Disease Control and PreventionMarshal Ma - Pennsylvania Department of HealthYong Long - Drexel UniversityCraig J. Newschaffer - Drexel University
- Publication Details
- International journal of stroke, v 8(SA100), pp 50-61
- Publisher
- Sage
- Number of pages
- 12
- Grant note
- Social Security Administration NIA; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA) U01AG009740 / NATIONAL INSTITUTE ON AGING; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA) NIA U01AG009740 / NIA; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics; A.J. Drexel Autism Institute
- Web of Science ID
- WOS:000328729500007
- Scopus ID
- 2-s2.0-84886286331
- Other Identifier
- 991019168128004721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Clinical Neurology
- Peripheral Vascular Disease