Journal article
Spatial and environmental correlates of organism colonization and infection in the neonatal intensive care unit
Journal of perinatology, v 38(5), pp 567-573
01 May 2018
PMID: 29255192
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objective To examine organism colonization and infection in the neonatal intensive care unit as a result of environmental and spatial factors.
Study design A retrospective cohort of infants admitted between 2006 and 2015 (n = 11 428), to assess the relationship between location and four outcomes: methicillin-resistant Staphylococcus aureus (MRSA) colonization; culture-confirmed late-onset sepsis; and, if intubated, endotracheal tube colonization with Pseudomonas aeruginosa or Klebsiella pneumonia. Independent risk factors were identified with mixed-effects logistic regression models and Moran's I for spatial autocorrelation.
Result All four outcomes statistically clustered by location; neighboring colonization also influenced risk of MRSA (p < 0.05). For P. aeruginosa, being in a location with space for more medical equipment was associated with 2.61 times the odds of colonization (95% CrI: 1.19, 5.78).
Conclusion Extrinsic factors partially explained risk for neonatal colonization and infection. For P. aeruginosa, infection prevention efforts at locations with space for more equipment may lower future colonization.
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Details
- Title
- Spatial and environmental correlates of organism colonization and infection in the neonatal intensive care unit
- Creators
- Neal D. Goldstein - Christiana Care Health SystemDeborah Tuttle - Christiana Care Health SystemLoni P. Tabb - Drexel UniversityDavid A. Paul - Christiana Care Health SystemStephen C. Eppes - Christiana Care Health System
- Publication Details
- Journal of perinatology, v 38(5), pp 567-573
- Publisher
- Springer Nature
- Number of pages
- 7
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative; Epidemiology and Biostatistics
- Web of Science ID
- WOS:000435108700021
- Scopus ID
- 2-s2.0-85038407550
- Other Identifier
- 991019168683204721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Obstetrics & Gynecology
- Pediatrics