Logo image
Spatial control of exocytosis
Journal article   Open access   Peer reviewed

Spatial control of exocytosis

Elias T Spiliotis and W James Nelson
Current opinion in cell biology, v 15(4), pp 430-437
Aug 2003
PMID: 12892783
url
https://doi.org/10.1016/S0955-0674(03)00074-7View
Published, Version of Record (VoR) Open

Abstract

Animals Carrier Proteins - metabolism Cell Membrane Structures - metabolism Transport Vesicles - metabolism Humans Cytoskeleton - metabolism Signal Transduction - physiology Cell Membrane - metabolism Membrane Fusion - physiology Exocytosis - physiology Intracellular Membranes - metabolism
During many key biological processes, exocytosis is confined to distinct regions of the plasma membrane. Spatial control of exocytosis correlates with altered membrane skeleton dynamics and assembly of local membrane microdomains. These domains act as local stages for the assembly and the regulation of molecular complexes (targeting patches) that mediate vesicle-membrane fusion. Furthermore, local activation of signaling pathways reinforces formation of these patches and might effect global repositioning of the secretory pathway toward sites of localized exocytosis.

Metrics

10 Record Views
32 citations in Scopus

Details

UN Sustainable Development Goals (SDGs)

This publication has contributed to the advancement of the following goals:

#3 Good Health and Well-Being

InCites Highlights

Data related to this publication, from InCites Benchmarking & Analytics tool:

Web of Science research areas
Cell Biology
Logo image