Journal article
Spike Timing, Spike Count, and Temporal Information for the Discrimination of Tactile Stimuli in the Rat Ventrobasal Complex
The Journal of neuroscience, v 29(18), pp 5964-5973
06 May 2009
PMID: 19420262
Abstract
The aim of this work was to investigate the role of spike timing for the discrimination of tactile stimuli in the thalamic ventrobasal complex of the rat. We applied information-theoretic measures and computational experiments on neurophysiological data to test the ability of single-neuron responses to discriminate stimulus location and stimulus dynamics using either spike count (40 ms bin size) or spike timing (1 ms bin size). Our main finding is not only that spike timing provides additional information over spike count alone, but specifically that the temporal aspects of the code can be more informative than spike count in the rat ventrobasal complex. Virtually all temporal information-i.e., information exclusively related to when the spikes occur-is conveyed by first spikes, arising mostly from latency differences between the responses to different stimuli. Although the imprecision of first spikes (i.e., the jitter) is highly detrimental for the information conveyed by latency differences, jitter differences can contribute to temporal information, but only if latency differences are close to zero. We conclude that temporal information conveyed by spike timing can be higher than spike count information for the discrimination of somatosensory stimuli in the rat ventrobasal complex.
Metrics
Details
- Title
- Spike Timing, Spike Count, and Temporal Information for the Discrimination of Tactile Stimuli in the Rat Ventrobasal Complex
- Creators
- G. Foffani - Servicio de Salud de Castilla La ManchaM. L. Morales-Botello - Hosp Nacl Paraplejicos, Serv Salud Castilla Mancha, Neurosignals Grp, Toledo 45071, SpainJ. Aguilar - Hosp Nacl Paraplejicos, Serv Salud Castilla Mancha, Neurosignals Grp, Toledo 45071, Spain
- Publication Details
- The Journal of neuroscience, v 29(18), pp 5964-5973
- Publisher
- Soc Neuroscience
- Number of pages
- 10
- Grant note
- Fundacion para la Investigacion Sanitaria en Castilla-La Mancha (Spain) CP05/00311 PI05/2322 / Fondo de Investigacion Sanitaria del Instituto de Salud Carlos III del Ministerio de Sanidad; Instituto de Salud Carlos III PAI06 / ConsejerIa de Educacion y Ciencia de la Junta de Comunidades de Castilla-La Mancha
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:000265827900025
- Scopus ID
- 2-s2.0-65949103404
- Other Identifier
- 991019353621304721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Neurosciences