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Journal article
Staged Transcrusal and Transsphenoidal Endoscopic Resection of an Atypical Clival Melanoma: A Case Report and Literature Review
Skull base, v 20(5), pp 349-355
01 Sep 2010
PMID: 21358999
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Abstract
We present a case of an atypical clival meningeal melanoma treated with a multidisciplinary staged transcrusal and transsphenoidal endoscopic surgical approach. A 45-year-old woman presented with a 15-month history of visual symptoms, neck pain, and unsteadiness. Magnetic resonance imaging of the head revealed a clival mass with both intracranial and extracranial involvement. Endoscopic clival biopsy suggested a melanocytic tumor. Extensive imaging and dermatological workup did not demonstrate a primary source. A multidisciplinary staged surgical resection included a transcrusal approach to resect the intracranial component, followed by transsphenoidal endoscopic resection of the extracranial component. Postoperatively, she received adjuvant radiation. At 1 year following surgery, the patient retains full preservation of hearing, facial nerve function, and extraocular movements. To our knowledge, this is the first case report of a combined surgical approach for a primary clival meningitic melanoma.
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Details
- Title
- Staged Transcrusal and Transsphenoidal Endoscopic Resection of an Atypical Clival Melanoma: A Case Report and Literature Review
- Creators
- Navjot Chaudhary - Western UniversityAmanda Hu - Western UniversityBrian W. Rotenberg - Division of Neurosurgery, Department of Clinical Neurosciences, University of Western Ontario, London, Ontario, Canada Department of Otolaryngology, University of Western Ontario, London, Ontario, Canada Department of Pathology, University of Western Ontario, London, Ontario, Canada Department of Diagnostic Radiology, University of Western Ontario, London, Ontario, CanadaNeil Duggal - Division of Neurosurgery, Department of Clinical Neurosciences, University of Western Ontario, London, Ontario, Canada Department of Otolaryngology, University of Western Ontario, London, Ontario, Canada Department of Pathology, University of Western Ontario, London, Ontario, Canada Department of Diagnostic Radiology, University of Western Ontario, London, Ontario, CanadaChristopher J. Howlett - Division of Neurosurgery, Department of Clinical Neurosciences, University of Western Ontario, London, Ontario, Canada Department of Otolaryngology, University of Western Ontario, London, Ontario, Canada Department of Pathology, University of Western Ontario, London, Ontario, Canada Department of Diagnostic Radiology, University of Western Ontario, London, Ontario, CanadaRobert R. Hammond - Division of Neurosurgery, Department of Clinical Neurosciences, University of Western Ontario, London, Ontario, Canada Department of Otolaryngology, University of Western Ontario, London, Ontario, Canada Department of Pathology, University of Western Ontario, London, Ontario, Canada Department of Diagnostic Radiology, University of Western Ontario, London, Ontario, CanadaLorne Parnes - Division of Neurosurgery, Department of Clinical Neurosciences, University of Western Ontario, London, Ontario, Canada Department of Otolaryngology, University of Western Ontario, London, Ontario, Canada Department of Pathology, University of Western Ontario, London, Ontario, Canada Department of Diagnostic Radiology, University of Western Ontario, London, Ontario, CanadaSteve P. Lownie - Division of Neurosurgery, Department of Clinical Neurosciences, University of Western Ontario, London, Ontario, Canada Department of Otolaryngology, University of Western Ontario, London, Ontario, Canada Department of Pathology, University of Western Ontario, London, Ontario, Canada Department of Diagnostic Radiology, University of Western Ontario, London, Ontario, Canada
- Publication Details
- Skull base, v 20(5), pp 349-355
- Publisher
- Thieme Medical Publishers
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Otolaryngology (and Head and Neck Surgery)
- Web of Science ID
- WOS:000280836700007
- Scopus ID
- 2-s2.0-77955682304
- Other Identifier
- 991019299103304721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Clinical Neurology
- Otorhinolaryngology
- Surgery