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Staphylococcus aureus: A Continuously Evolving and Formidable Pathogen in the Neonatal Intensive Care Unit
Journal article   Peer reviewed

Staphylococcus aureus: A Continuously Evolving and Formidable Pathogen in the Neonatal Intensive Care Unit

Alison J. Carey and Sarah S. Long
Clinics in perinatology, v 37(3), pp 535-546
01 Sep 2010
PMID: 20813269

Abstract

Life Sciences & Biomedicine Obstetrics & Gynecology Pediatrics Science & Technology
Staphylococcus aureus is a continuously evolving and formidable pathogen that has been a problem for both healthy and sick neonates for decades. Much focus over the past 20 years has been on hospital-associated methicillinresistant S aureus (HA-MRSA); however, a global epidemic because of virulent community-associated MRSA (CA-MRSA) that has no "fitness cost" for carrying antibiotic-resistance genes has moved into neonatal intensive care units (NICUs). Recently, methicillin-susceptible S aureus has adopted some of the virulence factors of CA-MRSA and is an increasingly common cause of hospital-acquired infections in NICUs. This article reviews the changing epidemiology, clinical manifestations, and treatment of S aureus in neonates.

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Web of Science research areas
Obstetrics & Gynecology
Pediatrics
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