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Stem Cell Therapy in Neonatal Diseases
Journal article   Peer reviewed

Stem Cell Therapy in Neonatal Diseases

Ciprian P. Gheorghe and Vineet Bhandari
Indian journal of pediatrics, v 82(7), pp 637-641
01 Jul 2015
PMID: 25804318

Abstract

Life Sciences & Biomedicine Pediatrics Science & Technology
Common complications in neonates occur in almost every organ system in the neonatal intensive care unit. While a number of them have short-term effects, a few of them also have long-term consequences. Among the latter are bronchopulmonary dysplasia and necrotizing enterocolitis in premature neonates, and hypoxic ischemic encephalopathy in borderline preterm and term neonates. While medical advances have improved our understanding of the pathogenesis, therapies to effectively prevent and/or significantly ameliorate the severity of these disorders, and to decrease their associated mortality and morbidity have not been found. One promising approach to make a potential impact in the outcomes of these neonatal conditions is the use stem cells, specifically, mesenchymal stem cells. The authors briefly review the potential role of stem cell therapy in the above-mentioned neonatal diseases. They focus primarily on human clinical trials.

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Collaboration types
Domestic collaboration
Web of Science research areas
Pediatrics
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