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Stereo- and regioselective formation of silyl enol ethers via oxidation of vinyl anions
Journal article   Peer reviewed

Stereo- and regioselective formation of silyl enol ethers via oxidation of vinyl anions

Franklin A. Davis, G. Sankar Lal and Jia Wei
Tetrahedron letters, v 29(34), pp 4269-4272
1988

Abstract

Oxidation of E- and Z-vinyl lithiums with silyl peroxides 5 affords silyl enol ethers 3 in good to excellent yield with retention of configuration. This methodology represents a useful new procedure for the stereo- and regioselective synthesis of ketone enolates. Oxidation of E- and Z-vinyl lithium 2 with silyl peroxides affords silyl enol ethers 3 in good to excellent yield with retention of configuration. This methodology represents a useful new procedure for the stereo- and gegioselective synthesis of ketone enolates.

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Web of Science research areas
Chemistry, Organic
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