Journal article
Stereotactic Body Radiation Therapy for Gynecologic Malignancies: A Case-Based Radiosurgery Society Practice Review
Practical radiation oncology, v 14(3), pp 252-266
May 2024
PMID: 37875223
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The use of stereotactic body radiation therapy (SBRT) for gynecologic malignancies is controversial. We discuss certain circumstances when highly precise SBRT may be a useful tool to consider in the management of selected patients.
Case selection included the following scenarios, the first 2 with palliative intent, para-aortic nodal oligorecurrence of ovarian cancer, pelvic sidewall oligorecurrence of cervical cancer, and inoperable endometrial cancer boost after intensity modulated radiation to the pelvis treated with curative intent. Patient characteristics, fractionation, prescription dose, treatment technique, and dose constraints were discussed. Relevant literature to these cases was summarized to provide a framework for treatment of similar patients.
Treatment of gynecologic malignancies with SBRT requires many considerations, including treatment intent, optimal patient selection, fractionation selection, tumor localization, and plan optimization. Although other treatment paradigms including conventionally fractionated radiation therapy and brachytherapy remain the standard-of-care for definitive treatment of gynecologic malignancies, SBRT may have a role in palliative cases or those where high doses are not required due to the unacceptable toxicity that may occur with SBRT.
A case-based practice review was developed by the Radiosurgery Society to provide a practical guide to the common scenarios noted above affecting patients with gynecologic malignancies.
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Details
- Title
- Stereotactic Body Radiation Therapy for Gynecologic Malignancies: A Case-Based Radiosurgery Society Practice Review
- Creators
- Colton Ladbury - City Of Hope National Medical CenterMark H Sueyoshi - Tufts Medical CenterNellie M Brovold - Mayo Clinic in ArizonaRitesh Kumar - Rutgers, The State University of New JerseyTherese Y Andraos - The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research InstituteEmile Gogineni - The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research InstituteMinsun Kim - University of WashingtonAnn Klopp - The University of Texas MD Anderson Cancer CenterKevin Albuquerque - The University of Texas Southwestern Medical CenterCharles Kunos - University of KentuckyEric Leung - Sunnybrook Health Science CentreConstantine Mantz - Fondazione Ricerca TraslazionaleTithi Biswas - University Hospitals Cleveland Medical CenterSushil Beriwal - Allegheny Health NetworkWilliam Small, Jr - Universidad Loyola AndalucíaBeth Erickson - Medical College of WisconsinDavid Gaffney - Huntsman Cancer InstituteSimon S Lo - University of WashingtonAkila N Viswanathan - Johns Hopkins Medicine
- Publication Details
- Practical radiation oncology, v 14(3), pp 252-266
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine)
- Web of Science ID
- WOS:001238227500001
- Scopus ID
- 2-s2.0-85178271932
- Other Identifier
- 991021897382604721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Oncology
- Radiology, Nuclear Medicine & Medical Imaging