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Stimulation, Recording Potential and Antimicrobial Medical Catheter Coatings
Journal article   Open access   Peer reviewed

Stimulation, Recording Potential and Antimicrobial Medical Catheter Coatings

Richard B. Beard, Mark DeLaurent, Kambiz Pourrezaei and Sorin Adrian
Metal-based drugs, v 1(5-6), pp 445-458
01 Jan 1994
PMID: 18476262
url
https://doi.org/10.1155/mbd.1994.445View
Published, Version of Record (VoR)CC BY V4.0 Open
url
https://doi.org/10.1155/MBD.1994.445View
Published, Version of Record (VoR) Open

Abstract

Biocompatibility of electrodes for stimulation are difficult to maintain homeostasis. Noble metal stimulating electrodes which are normally biocompatible on keratinized tissue become very non-biocompatible when they are interfaced with nonkeratinized tissue in an area such as the oral cavity. Composite electrodes have been made biocompatible in the oral cavity even at current densities larger than 1 μA/ mm 2 . Electrodes used in potential readings require that the anodic and cathodic polarization remain minimal. Silver-silver chloride electrodes are minimal. Silver-silver chloride electrodes are not always reversible. The range of pH, voltages and current densities when silver-silver chloride are not reversible are presented. Recently at Drexel University reliable silver coatings inside and outside of medical catheters have been fabricated to act as antimicrobial to a variety of bacteria. Noble and nonnoble metals have been combined in coatings with silver to enhance the antimicrobial action.

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