Journal article
Subacute Sclerosing Panencephalitis (SSPE) Presenting as Acute Disseminated Encephalomyelitis in a Child
Journal of child neurology, v 24(7), pp 899-903
01 Jul 2009
PMID: 19204320
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Subacute sclerosing panencephalitis (SSPE) typically presents with progressive mental deterioration, behavioral changes, and myoclonic jerks. Atypical presentations are not unknown and may result in diagnostic delays. A 9-year-old girl presented with poor balance and ataxia following an episode of upper respiratory tract infection. Neurological examination revealed mild hemiparesis and ataxia. Brain magnetic resonance imaging revealed scattered areas of T2 and fluid-attenuated inversion recovery hyperintensities in the white matter consistent with acute disseminated encephalomyelitis. Despite treatment with intravenous methylprednisolone, intravenous immunoglobulins, and plasmapheresis, progressive neurological worsening Occurred. Later during the Course of her illness, subacute sclerosing panencephalitis was suspected from the appearance of burst-suppression pattern on electroencephalogram, and the diagnosis confirmed by elevated titers of measles antibodies in cerebrospinal fluid. Physicians taking care of children need to be aware of atypical presentations of subacute sclerosing panencephalitis and must have a high index Of Suspicion to prevent diagnostic delays and avoid unnecessary diagnostic and therapeutic interventions.
Metrics
Details
- Title
- Subacute Sclerosing Panencephalitis (SSPE) Presenting as Acute Disseminated Encephalomyelitis in a Child
- Creators
- Jatinder Goraya - St. Christopher's Hospital for ChildrenHarold Marks - St. Christopher's Hospital for ChildrenDivya Khurana - St. Christopher's Hospital for ChildrenAgustin Legido - St. Christopher's Hospital for ChildrenJoseph Melvin - St. Christopher's Hospital for Children
- Publication Details
- Journal of child neurology, v 24(7), pp 899-903
- Publisher
- Sage
- Number of pages
- 5
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pediatrics
- Web of Science ID
- WOS:000267347000021
- Scopus ID
- 2-s2.0-67949109655
- Other Identifier
- 991019168434704721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Clinical Neurology
- Pediatrics