Journal article
Subharmonic signal generation from contrast agents in simulated neovessels
Ultrasound in medicine & biology, v 30(2), pp 199-203
2004
PMID: 14998672
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Detection and measurement of blood flow in neovessels around a tumor can yield prognostic information about the tumor. Early detection and classification may help differentiate benign and malignant tumors; thus, improving patient management. This can be accomplished by injecting ultrasonic contrast agents and measuring the backscattered signals from them. Use of the subharmonic backscattered signals from these agents may be better than fundamental or second harmonic components because of the negligible subharmonics generated by the surrounding tissue. Preliminary results on the detection and measurement of subharmonic signal components up to 12 dB (at increasing pressures) from very small tubes (200 to 300 μm diameter) are reported, demonstrating the possibility and potential application of subharmonic imaging in detecting tumor angiogenesis. (E-mail: pshankar@coe.drexel.edu)
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Details
- Title
- Subharmonic signal generation from contrast agents in simulated neovessels
- Creators
- Govind Bhagavatheeshwaran - School of Biomedical Engineering, Sciences and Health Systems, Drexel University, Philadelphia, PA, USAWilliam T Shi - Department of Radiology, Thomas Jefferson University, Philadelphia, PA, USAFlemming Forsberg - Department of Radiology, Thomas Jefferson University, Philadelphia, PA, USAP.M Shankar - School of Biomedical Engineering, Sciences and Health Systems, Drexel University, Philadelphia, PA, USA
- Publication Details
- Ultrasound in medicine & biology, v 30(2), pp 199-203
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Electrical and Computer Engineering; School of Biomedical Engineering, Science, and Health Systems
- Web of Science ID
- WOS:000189348600009
- Scopus ID
- 2-s2.0-1442348365
- Other Identifier
- 991014878119904721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Acoustics
- Radiology, Nuclear Medicine & Medical Imaging