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Successful treatment of acute left ventricular assist device thrombosis and cardiogenic shock with intraventricular thrombolysis and a tandem heart
Journal article   Open access   Peer reviewed

Successful treatment of acute left ventricular assist device thrombosis and cardiogenic shock with intraventricular thrombolysis and a tandem heart

Richa Agarwal, Amresh Raina, David M Lasorda, Robert J Moraca, Stephen H Bailey, Manreet Kanwar, George Sokos, Srinivas Murali and Raymond L Benza
ASAIO journal (1992), v 61(1), pp 98-101
Jan 2015
DOI: https://doi.org/10.1097/MAT.0000000000000149
PMID: 25248042
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1097/MAT.0000000000000149View
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Abstract

Adult Female Fibrinolytic Agents - therapeutic use Heart-Assist Devices - adverse effects Humans Prosthesis Failure Shock, Cardiogenic - drug therapy Shock, Cardiogenic - etiology Shock, Cardiogenic - therapy Thrombolytic Therapy Thrombosis - drug therapy Thrombosis - etiology Thrombosis - therapy Tissue Plasminogen Activator - therapeutic use
Management for continuous flow left ventricular assist device (LVAD) thrombosis often relies on speculation of individual clinical risk factors and integration of indirect evidence for device dysfunction. There are no comprehensive guidelines for treatment of this serious complication, and most of our current knowledge comes from anecdotal experience or observational study. More data on effective treatment, both with aggressive pharmacologic and device-based interventions, are needed for improving our understanding of mechanisms driving device thrombosis and for preventing future events. We present a case of LVAD thrombosis with emphasis on recognition and treatment of acute pump thrombosis, and discuss a potentially novel strategy using percutaneous mechanical circulatory support for pump salvage.

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7 Record Views
6 citations in Web of Science
6 citations in Scopus

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UN Sustainable Development Goals (SDGs)

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#3 Good Health and Well-Being

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Web of Science research areas
Engineering, Biomedical
Transplantation
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