Journal article
Summary of NIH Medical-Surgical Emergency Research Roundtable Held on April 30 to May 1, 2009
Annals of emergency medicine, v 56(5), pp 522-537
01 Nov 2010
PMID: 21036293
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Study objective: In 2003, the Institute of Medicine Committee on the Future of Emergency Care in the United States Health System convened and identified a crisis in emergency care in the United States, including a need to enhance the research base for emergency care. As a result, the National Institutes of Health (NIH) formed an NIH Task Force on Research in Emergency Medicine to enhance NIH support for emergency care research. Members of the NIH Task Force and academic leaders in emergency care participated in 3 roundtable discussions to prioritize current opportunities for enhancing and conducting emergency care research. The objectives of these discussions were to identify key research questions essential to advancing the scientific underpinnings of emergency care and to discuss the barriers and best means to advance research by exploring the role of research networks and collaboration between the NIH and the emergency care community.
Methods: The Medical-Surgical Research Roundtable was convened on April 30 to May 1, 2009. Before the roundtable, the emergency care domains to be discussed were selected and experts in each of the fields were invited to participate in the roundtable. Domain experts were asked to identify research priorities and challenges and separate them into mechanistic, translational, and clinical categories. After the conference, the lists were circulated among the participants and revised to reach a consensus.
Results: Emergency care research is characterized by focus on the timing, sequence, and time sensitivity of disease processes and treatment effects. Rapidly identifying the phenotype and genotype of patients manifesting a specific disease process and the mechanistic reasons for heterogeneity in outcome are important challenges in emergency care research. Other research priorities include the need to elucidate the timing, sequence, and duration of causal molecular and cellular events involved in time-critical illnesses and injuries, and the development of treatments capable of halting or reversing them; the need for novel animal models; and the need to understand why there are regional differences in outcome for the same disease processes. Important barriers to emergency care research include a limited number of trained investigators and experienced mentors, limited research infrastructure and support, and regulatory hurdles. The science of emergency care may be advanced by facilitating the following: (1) training emergency care investigators with research training programs; (2) developing emergency care clinical research networks; (3) integrating emergency care research into Clinical and Translational Science Awards; (4) developing emergency-care specific initiatives within the existing structure of NIH institutes and centers; (5) involving emergency specialists in grant review and research advisory processes; (6) supporting learn-phase or small, clinical trials; and (7) performing research to address ethical and regulatory issues.
Conclusion: Enhancing the research base supporting the care of medical and surgical emergencies will require progress in specific mechanistic, translational, and clinical domains; effective collaboration of academic investigators across traditional clinical and scientific boundaries; federal support of research in high-priority areas; and overcoming limitations in available infrastructure, research training, and access to patient populations. [Ann Emerg Med. 2010;56:522-537.]
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Details
- Title
- Summary of NIH Medical-Surgical Emergency Research Roundtable Held on April 30 to May 1, 2009
- Creators
- Amy H. Kaji - College Station Medical CenterRoger J. Lewis - College Station Medical CenterTony Beavers-May - Arkansas Childrens Hosp, Microbiol Lab, Little Rock, AR 72202 USARobert Berg - College Station Medical CenterEileen Bulger - University of WashingtonCharles Cairns - College Station Medical CenterClifton Callaway - University of PittsburghCarlos A. Camargo - College Station Medical CenterJoseph Carcillo - University of PittsburghRoberta DeBiasi - College Station Medical CenterTania DiazFrancine Ducharme - Université de MontréalSeth Glickman - College Station Medical CenterKatherine HeilpernRobert Hickey - College Station Medical CenterTerry Vanden Hoek - University of ChicagoJudd Hollander - College Station Medical CenterSusan Janson - Univ Calif San Francisco, San Francisco, CA 94143 USAGregory Jurkovich - University of WashingtonArthur Kellermann - Emory UniversityStephen Kingsmore - Natl Ctr Genome Resources, Santa Fe, NM 87505 USAJeffrey Kline - College Station Medical CenterNathan Kuppermann - College Station Medical CenterRobert Lowe - College Station Medical CenterDavid McLario - College Station Medical CenterLarry Nathanson - College Station Medical CenterGraham Nichol - University of WashingtonAndrew Peitzman - University of PittsburghLynne Richardson - College Station Medical CenterArthur Sanders - University of ArizonaManish Shah - University of RochesterNathan Shapiro - College Station Medical CenterRobert Silverman - College Station Medical CenterMartin Than - Christchurch Publ Hosp, Emergency Dept, Christchurch 4710, New ZealandScott Wilber - Ohio UniversityDonald M. Yealy - University of PittsburghRoundtable Steering Comm
- Publication Details
- Annals of emergency medicine, v 56(5), pp 522-537
- Publisher
- Elsevier
- Number of pages
- 16
- Grant note
- Clinical and Translational Science NIH Institutes and Centers; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:000284292800018
- Scopus ID
- 2-s2.0-78049479617
- Other Identifier
- 991021463605504721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Emergency Medicine