Journal article
Surfactant: clinical applications
American family physician, v 46(1), pp 233-236
Jul 1992
PMID: 1621634
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Pulmonary surfactant is an important chemical component of the lung. It decreases surface tension in the alveolar cells to help stabilize the alveoli, and it may help prevent pulmonary edema. Currently, naturally and synthetically derived surfactants are being used to treat neonatal respiratory distress syndrome, a leading cause of death in premature infants. Surfactant is recommended for prophylactic therapy in infants weighing less than 1,350 g (3 lb) and in infants weighing more than 1,350 g who show signs of pulmonary immaturity and for rescue therapy in infants with respiratory distress syndrome. Surfactant is administered by endotracheal tube, and the recommended dose is 5 mg per kg. Three doses, given 12 hours apart, is the recommended regimen for prophylactic therapy. Rescue therapy consists of one dose of surfactant given at the onset of respiratory distress and another dose given 12 hours later.
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Details
- Title
- Surfactant: clinical applications
- Creators
- C D Patton - Hahnemann University School of Medicine, Philadelphia, PennsylvaniaE S Schulman
- Publication Details
- American family physician, v 46(1), pp 233-236
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pulmonary, Critical Care, and Sleep (Medicine)
- Web of Science ID
- WOS:A1992JD74300021
- Scopus ID
- 2-s2.0-0026748671
- Other Identifier
- 991019184309504721
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- Web of Science research areas
- Primary Health Care