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Journal article
Surgery Versus Radiation Therapy for Stage IB2 Cervical Carcinoma A Population-Based Analysis
International journal of gynecological cancer, v 22(3), pp 484-489
01 Mar 2012
PMID: 22249576
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objective: The objective of the study was to examine outcomes in stage IB2 cervical cancer patients undergoing primary surgery versus radiation.
Methods: Stage IB2 cervical cancer patients were identified from the Surveillance, Epidemiology and End Results Public-Use Database from 2000 to 2006. Patients were divided into those receiving radiation (radiation first) or surgery (surgery first) as initial treatment. Overall survival was calculated by Kaplan-Meier method and compared using log-rank test.
Results: In total, 770 patients were identified with stage IB2 cervical cancer; 369 received radiation, and 401 received surgery initially. The radiation-first group had larger mean tumor size than the surgery-first group (6.0 vs 5.5 cm, respectively; P < 0.0001). The overall survival was longer in the surgery-first group compared with the radiation-first group (72.0 vs 61.4 months, respectively; P < 0.0001).
Conclusions: Patients undergoing surgery as initial treatment for stage IB2 cervical cancer appear to have improved outcomes in the current era of chemoradiation; however, given the lack of chemotherapy information, a randomized trial will be necessary to see if these results remain valid.
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Details
- Title
- Surgery Versus Radiation Therapy for Stage IB2 Cervical Carcinoma A Population-Based Analysis
- Creators
- Bunja Rungruang - Magee-Womens HospitalMadeleine Courtney-Brooks - Magee-Womens HospitalSushil Beriwal - Magee-Womens HospitalKristin K. Zorn - Magee-Womens HospitalScott D. Richard - Magee-Womens HospitalAlexander B. Olawaiye - Magee-Womens HospitalThomas C. Krivak - Magee-Womens HospitalPaniti Sukumvanich (Corresponding Author) - Magee-Womens Hospital
- Publication Details
- International journal of gynecological cancer, v 22(3), pp 484-489
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 6
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Radiation Oncology (and Nuclear Medicine); Obstetrics and Gynecology
- Web of Science ID
- WOS:000300735900023
- Scopus ID
- 2-s2.0-84858204140
- Other Identifier
- 991021897270304721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Obstetrics & Gynecology
- Oncology