Journal article
Sweet connections: O-GlcNAcylation links cancer cell metabolism and survival
Molecular & cellular oncology, v 2(1), pp e961809-e961809
02 Jan 2015
PMID: 27308381
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Increased O-GlcNAcylation is emerging as a general characteristic of cancer cells that is critical for multiple oncogenic phenotypes. Recently, we demonstrated that elevated O-GlcNAcylation contributes to the metabolic shift seen in cancer through stabilization of the glycolytic regulator HIF-1α and links metabolism to stress and cancer cell survival.
Metrics
Details
- Title
- Sweet connections: O-GlcNAcylation links cancer cell metabolism and survival
- Creators
- Christina M Ferrer - Department of Biochemistry and Molecular Biology; Drexel University College of MedicineMauricio J Reginato - Department of Biochemistry and Molecular Biology; Drexel University College of Medicine
- Publication Details
- Molecular & cellular oncology, v 2(1), pp e961809-e961809
- Publisher
- Taylor & Francis
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Biochemistry and Molecular Biology
- Web of Science ID
- WOS:000218549300018
- Scopus ID
- 2-s2.0-85021735863
- Other Identifier
- 991014877677704721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Oncology