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Journal article
Symptoms of autism spectrum disorder and developmental delay in children with low mental age
Clinical neuropsychologist, v 36(5), pp 1028-1048
04 Jul 2022
PMID: 34762009
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objective: Autism spectrum disorder (ASD) in very young children with significant cognitive impairment is difficult to diagnose, depriving them of the earliest opportunities for autism-specific intervention. This study delineated specific symptoms in this group, compared to symptoms in children with Global Developmental Delay (GDD) and in ASD with milder developmental delays.Method: Autism Diagnostic Observation Schedule, 2nd Edition, Toddler Module revealed symptoms in three groups of toddlers, with mean ages of 17-20 months: (1) ASD and cognitive/language functioning below the 12-month level (ASD-MA < 12 mos; n = 28), (2) GDD (n = 27), and (3) ASD and cognitive/language functioning at or above the 12-month level (ASD-MA ≥ 12 mos; n = 29). Logistic regression models were fit to control for developmental level. Results: Items in all domains (social interaction, communication, repetitive movements) discriminated ASD-MA < 12 mos from GDD. The two ASD groups, matched for age but differing on developmental level, showed strikingly similar ASD symptomatology. Conclusion: ADOS-2 symptoms differentiated ASD-MA < 12 mos from GDD, after controlling for cognitive impairment. Symptoms in the two ASD groups were minimally related to developmental level. The ADOS-2 Toddler Module successfully captured ASD symptomatology even in children whose developmental level was below the recommended ADOS-2 cutoff of 12 months, which may increase their access to early ASD-specific intervention.
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Details
- Title
- Symptoms of autism spectrum disorder and developmental delay in children with low mental age
- Creators
- Rebecca P. Thomas - University of ConnecticutStephanie Milan - University of ConnecticutLetitia Naigles - University of ConnecticutDiana L. Robins - Drexel UniversityMarianne L. Barton - University of ConnecticutLauren B. Adamson - Georgia State UniversityDeborah A. Fein - University of Connecticut
- Publication Details
- Clinical neuropsychologist, v 36(5), pp 1028-1048
- Publisher
- Routledge
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- A.J. Drexel Autism Institute
- Web of Science ID
- WOS:000717391600001
- Scopus ID
- 2-s2.0-85119212079
- Other Identifier
- 991019169594104721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Psychology
- Psychology, Clinical