Journal article
Synergism of Short-Term Air Pollution Exposures and Neighborhood Disadvantage on Initial Stroke Severity
Stroke (1970), v 48(11), pp 3126-3129
01 Nov 2017
PMID: 28954921
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background and Purpose-Little is known about the relation between environment and stroke severity. We investigated associations between environmental exposures, including neighborhood socioeconomic disadvantage and short-term exposure to airborne particulate matter <2.5 mu m and ozone, and their interactions with initial stroke severity.
Methods-First-ever ischemic stroke cases were identified from the Brain Attack Surveillance in Corpus Christi project (2000-2012). Associations between pollutants, disadvantage, and National Institutes of Health Stroke Scale were modeled using linear and logistic regression with adjustment for demographics and risk factors. Pollutants and disadvantage were modeled individually, jointly, and with interactions.
Results-Higher disadvantage scores and previous-day ozone concentrations were associated with higher odds of severe stroke. Higher levels of particulate matter <2.5 mu m were associated with higher odds of severe stroke among those in higher disadvantage areas (odds ratio, 1.24; 95% confidence interval, 1.00-1.55) but not in lower disadvantage areas (odds ratio, 0.82; 95% confidence interval, 0.56-1.22; P interaction = 0.097).
Conclusions-Air pollution exposures and neighborhood socioeconomic status may be important in understanding stroke severity. Future work should consider the multiple levels of influence on this important stroke outcome.
Metrics
Details
- Title
- Synergism of Short-Term Air Pollution Exposures and Neighborhood Disadvantage on Initial Stroke Severity
- Creators
- Jeffrey J. Wing - University of MichiganBrisa N. Sanchez - University of MichiganSara D. Adar - University of MichiganWilliam J. Meurer - Univ Michigan, Stroke Program, Dept Neurol, Ann Arbor, MI 48109 USALewis B. Morgenstern - University of MichiganMelinda A. Smith - Univ Michigan, Stroke Program, Dept Neurol, Ann Arbor, MI 48109 USALynda D. Lisabeth - University of Michigan
- Publication Details
- Stroke (1970), v 48(11), pp 3126-3129
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 8
- Grant note
- R01NS038916 / NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) R01 NS38916 / National Institutes of Health/National Institute of Neurological Disorders and Stroke; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Epidemiology and Biostatistics
- Web of Science ID
- WOS:000413496900042
- Scopus ID
- 2-s2.0-85032148959
- Other Identifier
- 991020100076704721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Clinical Neurology
- Peripheral Vascular Disease