Journal article
Synthesis and Evaluation of an 111In-labeled Porphyrin for Lymph Node Imaging
Journal of pharmaceutical sciences, v 71(11), pp 1223-1226
Nov 1982
PMID: 7175713
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
111In-labeled tetra(4-N-methylpyridyl) porphyrin was investigated as a possible lymph node imaging agent. A clinically feasible method for the preparation of this radioactive pharmaceutical was developed from experiments with the synthesis and characterization of the unlabeled complex. The in vivo distribution of the compound in Wistar rats was determined as a function of time. Favorable lymph node-blood, lymph node-muscle, and specific lymph node-surrounding tissue ratios were obtained.
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Details
- Title
- Synthesis and Evaluation of an 111In-labeled Porphyrin for Lymph Node Imaging
- Creators
- Richard Vaum - Drexel UniversityNed D. Heindel - Lehigh UniversityH. Donald Burns - Drexel UniversityJacqueline Emrich - Drexel UniversityNatalie Foster - Lehigh University
- Publication Details
- Journal of pharmaceutical sciences, v 71(11), pp 1223-1226
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:A1982PQ57900010
- Scopus ID
- 2-s2.0-0020333540
- Other Identifier
- 991019184096604721
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InCites Highlights
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Chemistry, Medicinal
- Chemistry, Multidisciplinary
- Pharmacology & Pharmacy