Journal article
Synthesis and characterization of electro-active and biodegradable block copolymer of aniline pentamer with polylactide
Gāoděng xuéxiào huàxué xuébaò, Vol.26(9), pp.1771-1773
10 Sep 2005
Abstract
Every slight movement of human body, such as beat of heart, contract of muscles, thinking of brain, is associated with bioelectricity. In search for a neural conducting tissue engineering material which can ideally conduct bioelectrical signals in vivo, the block copolymer of polylactide(PLA) and aniline pentamer - a material which is electro-active, remarkably biocompatible and biodegradable, was designed and synthesized. The aniline pentamer is similar with polyaniline in electrical chemical properties, but more soluble than the latter. The copolymer is prepared by condensation polymerization between carboxyl-capped aniline pentamer and dihydroxyl-capped PLA, with N,N '-dicyclohexylcarbodiimide (DCC) as a condensing agent. The co-polymerization of aniline pentarner and PIA can not only reduce the toxicity of aniline pentamer, but also make the material easily to degrade and excrete from the body. These properties of the copolymer provide a favorable prospect in biomedical application in vivo. The synthesize
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Details
- Title
- Synthesis and characterization of electro-active and biodegradable block copolymer of aniline pentamer with polylactide
- Creators
- L H HuangJ HuX L ZhuangJ MaX S ChenX B JingY GuoM Y LiP I LelkesY Wei
- Publication Details
- Gāoděng xuéxiào huàxué xuébaò, Vol.26(9), pp.1771-1773
- Publisher
- Higher Education Press
- Number of pages
- 3
- Resource Type
- Journal article
- Language
- Chinese
- Academic Unit
- Mathematics
- Identifiers
- 991019170344004721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Chemistry, Multidisciplinary