Journal article
Synthesis of (2 R, 3 S)-methyl-2-fluoro-3-(n-benzoylamino)-3-phenylpropanoate: Modified side chain of taxol
Tetrahedron: asymmetry, v 5(6), pp 955-960
1994
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Methyl-2-fluoro-3-(N-benzoylamino)-3-phenylpropanoate
2 and
3, fluorine analogs of the C-13 side chain of taxol, were synthesized by electrophilic fluorination of the dianion of methyl (
R)-(−)-(N-benzoyl)-3-amino-3-phenylpropanoale (
4).
Methyl-2-fluoro-3-(N-benzoylamino)-3-phenylpropanoate
2 and
3, fluorine analogs of the C-13 side chain of taxol, were synthesized by electrophilic fluorination of the dianion of methyl (
R)-(−)-benzoyl)-3-amino-3-phenylpropanoate (
4) with NFOBS
6.
Metrics
Details
- Title
- Synthesis of (2 R, 3 S)-methyl-2-fluoro-3-(n-benzoylamino)-3-phenylpropanoate: Modified side chain of taxol
- Creators
- Franklin A. Davis - Drexel UniversityRajarathnam E. Reddy - Drexel University
- Publication Details
- Tetrahedron: asymmetry, v 5(6), pp 955-960
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:A1994NU92500002
- Scopus ID
- 2-s2.0-0028306239
- Other Identifier
- 991019173986004721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Chemistry, Inorganic & Nuclear
- Chemistry, Organic
- Chemistry, Physical