Journal article
Systems-level questions in Drosophila oogenesis
Systems biology, v 152(4), pp 276-284
Dec 2005
PMID: 16986271
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
This paper describes computational and experimental work on pattern formation in Drosophila egg development (oogenesis), an established experimental model for studying cell fate diversification in developing tissues. Epidermal growth factor receptor (EGFR) is a key regulator of pattern formation and morphogenesis in Drosophila oogenesis. EGFR signalling in oogenesis can be genetically manipulated and monitored at many levels, leading to large sets of heterogeneous data that enable the formulation of increasingly quantitative models of pattern formation in these systems.
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Details
- Title
- Systems-level questions in Drosophila oogenesis
- Creators
- N Yakoby - Lewis-Sigler Institute for Integrative Genomics and Department of Chemical Engineering, Princeton University, USAC A BristowI GouzmanM P RossiY GogotsiT SchüpbachS Y Shvartsman
- Publication Details
- Systems biology, v 152(4), pp 276-284
- Publisher
- England
- Grant note
- P01-CA41086 / NCI NIH HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Materials Science and Engineering
- Web of Science ID
- WOS:000235323900018
- Scopus ID
- 2-s2.0-31144475005
- Other Identifier
- 991014878345804721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Cell Biology
- Mathematical & Computational Biology