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Systolic Blood Pressure Trends in US Adults between 1960 and 1980 Influence of Antihypertensive Drug Therapy
Journal article   Open access   Peer reviewed

Systolic Blood Pressure Trends in US Adults between 1960 and 1980 Influence of Antihypertensive Drug Therapy

Shiriki K. Kumanyika, J. Richard Landis, Yvonne L. Matthews-Cook, Susan L. Almy and Susan J. Shirk Boehmer
American journal of epidemiology, v 148(6), pp 528-538
15 Sep 1998
PMID: 9753007
Featured in Collection :   UN Sustainable Development Goals @ Drexel
url
https://doi.org/10.1093/oxfordjournals.aje.a009678View
Published, Version of Record (VoR)Maybe Open Access (Publisher Bronze) Open

Abstract

antihypertensive agents blacks blood pressure body weight ethnic groups hypertension obesity
Recent blood pressure trends reflect progress in hypertension control, but prevalent drug therapy precludes direct estimation of the component due to primary prevention. In data gathered on persons aged 35–74 years in three successive US health examination surveys (1960–1980), systolic blood pressure levels assuming no drug therapy were imputed by reassigning blood pressure to the upper end of the distribution for respondents reporting use of antihypertensive medication. Blood pressure was partitioned into four ordinal categories based on weighted percentiles of the 1960–1962 distributions for 35- to 44-year-old males and females who reported no use of antihypertensive medication. Cumulative logit models (α = 0.01) were used to estimate age-and sex-specific trends for blacks and whites within two strata (<25 or ≥25) of body mass index (BMI) (weight (kg)/height (m)2). Before imputation, systolic blood pressure decreased between 1960 and 1980; after imputation, significant decreases remained only in 35- to 44-year-old. Strong associations of black race and BMI ≥25 with higher blood pressures were present in models with and without drug therapy. Thus, according to the models, there has been little progress in decreasing racial or BMI-related blood pressure differentials. Above the age of 44 years, blood pressure trends were largely attributable to medication use. In contrast, data for 35- to 44-year-olds suggest progress in primary prevention. Am J Epidemiol 1998;148:528–38.

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Public, Environmental & Occupational Health
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