Journal article
T-cell receptor excision circles (TREC) and maintenance of long-term non-progression status in HIV-1 infection
AIDS (London), Vol.17(6), pp.915-916
11 Apr 2003
Abstract
T-cell receptor excision circles (TREC) in peripheral blood mononuclear cells (PBMC) were evaluated in the Genetic Resistance to Human Immunodeficiency Virus cohort of HIV-1-seropositive non-progressors (NP). After a short follow-up, NP were sub-grouped as stable (NP-S), or with signs of disease progression (NP-P). Initial TREC were higher in NP-S compared to NP-P (P = 0.002), even after adjusting for CD4 and CD8 T-cell counts and viral load (P = 0.048), but not p24 antigenemia (P = 0.076). Higher initial TREC were 100% predictive of the maintenance of non-progression status during follow-up.
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Details
- Title
- T-cell receptor excision circles (TREC) and maintenance of long-term non-progression status in HIV-1 infection
- Creators
- M W RichardsonA E SverstiukE J GracelyH HendelK KhaliliJ-F ZaguryJ Rappaport
- Publication Details
- AIDS (London), Vol.17(6), pp.915-916
- Publisher
- Lippincott
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- MD (Doctor of Medicine) Program
- Identifiers
- 991014878122304721