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Published, Version of Record (VoR)Open Access (License Unspecified), Open
Journal article
Temporal order of signal propagation within and across intrinsic brain networks
Proceedings of the National Academy of Sciences - PNAS, v 118(48), e2105031118
30 Nov 2021
PMID: 34819365
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
We studied the temporal dynamics of activity within and across functional MRI (fMRI)-derived nodes of intrinsic resting-state networks of the human brain using intracranial electroencephalography (iEEG) and repeated single-pulse electrical stimulation (SPES) in neurosurgical subjects implanted with intracranial electrodes. We stimulated and recorded from 2,133 and 2,372 sites, respectively, in 29 subjects. We found that N1 and N2 segments of the evoked responses are associated with intra- and internetwork communications, respectively. In a separate cognitive experiment, evoked electrophysiological responses to visual target stimuli occurred with less temporal separation across pairs of electrodes that were located within the same fMRI-defined resting-state networks compared with those located across different resting-state networks. Our results suggest intranetwork prior to internetwork information processing at the subsecond timescale.
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Details
- Title
- Temporal order of signal propagation within and across intrinsic brain networks
- Creators
- Mike J Veit - Stanford UniversityAaron Kucyi - Northeastern UniversityWenhan Hu - Beijing Tian Tan HospitalChao Zhang - Beijing Tian Tan HospitalBaotian Zhao - Beijing Tian Tan HospitalZhihao Guo - Beijing Tian Tan HospitalBowen Yang - Beijing Tian Tan HospitalClara Sava-Segal - Stanford UniversityClaire Perry - Stanford UniversityJianguo Zhang - Beijing Tian Tan HospitalKai Zhang - Beijing Tian Tan HospitalJosef Parvizi - Stanford University
- Publication Details
- Proceedings of the National Academy of Sciences - PNAS, v 118(48), e2105031118
- Publisher
- PNAS
- Grant note
- R21 NS113024 / NINDS NIH HHS CIHR
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychological and Brain Sciences (Psychology)
- Web of Science ID
- WOS:000723881800014
- Scopus ID
- 2-s2.0-85122169433
- Other Identifier
- 991021448046604721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Neurosciences