Journal article
Testing the efficacy of a culturally adapted family dementia caregiver intervention (REACH VN): Results from a cluster randomized controlled trial in Northern Vietnam
The American journal of geriatric psychiatry, v 33(5), pp P535-P545
May 2025
PMID: 39547823
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Abstract
•What is the primary question addressed by this study? This is a two-armed cluster randomized controlled trial to test the efficacy of a culturally adapted family caregiver intervention (REACH VN) in reducing caregiver psychological distress and caregiver burden in Vietnam.•What is the main finding of this study? Caregivers in the REACH VN intervention group had significantly lower psychological distress at 3 months and caregiving burden at 6 months compared to those in the control group. Secondary outcomes (perceived stress, somatic symptoms) were also significantly improved at 3 months but not at 6 months.•What is the meaning of the finding? REACH VN, a multicomponent intervention, is efficacious in supporting and improving the health of family dementia caregivers in Vietnam although further modifications may be needed to sustain effects after 3 months.
Vietnam faces an unprecedented increase in people living with dementia but lacks evidence-based family dementia caregiver interventions. We tested the efficacy of a culturally adapted family caregiver intervention (REACH VN) in Northern Vietnam.
In this randomized controlled trial, clusters (communes) were assigned to (1) REACH VN (a multicomponent intervention consisting of 4-6 one-hour sessions delivered over 1-3 months) or (2) enhanced control (one session of dementia education). Primary outcomes were caregiver perceived psychological distress (PHQ-4) and burden (ZBI-12). Secondary outcomes were caregiver perceived stress (PSS-10) and somatic symptoms (PHQ-15). Mixed effects analysis was performed with 3-month and 6-month assessments as the outcomes and baseline assessment as a covariate.
Overall, 350 caregivers from 40 clusters (21 intervention, 19 enhanced control) enrolled and 330 (94.3%) completed 3-month assessments. At 3 months, the REACH VN intervention group had lower PHQ-4 (p<0.001) but not ZBI-12 (p=0.05) scores compared to control. At 6 months, the intervention group had lower ZBI-12 (p=0.002) but not PHQ-4 (p=0.5) scores. PSS-10 and PHQ-15 scores were also improved at 3 months (p=0.007, p<0.001 respectively) for the REACH VN intervention group compared with control but not at 6 months.
REACH VN improved outcomes in family caregivers in Vietnam at 3 months although improvement was not sustained for most outcomes at 6 months.
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Details
- Title
- Testing the efficacy of a culturally adapted family dementia caregiver intervention (REACH VN): Results from a cluster randomized controlled trial in Northern Vietnam
- Creators
- Huong Nguyen - University of MinnesotaHung Trong Nguyen - Vietnam National Geriatric Hospital, Hanoi, VietnamNgoc Bich Nguyen - Vietnam National Geriatric Hospital, Hanoi, VietnamDuyen Tran - University of California, DavisDanielle J. Harvey - University of California, DavisBinh Thanh Nguyen - Vietnam National Geriatric Hospital, Hanoi, VietnamBinh Thi Thanh Nguyen - Vietnam National Geriatric Hospital, Hanoi, VietnamAnh Ngoc Nguyen - Vietnam National Geriatric Hospital, Hanoi, VietnamChinh Thi Hong Nguyen - Vietnam National Geriatric Hospital, Hanoi, VietnamThu Thi Hoai Nguyen - Vietnam National Geriatric Hospital, Hanoi, VietnamThuy Le Nguyen - Vietnam National Geriatric Hospital, Hanoi, VietnamAnh Thi Phuong Nguyen - Vietnam National Geriatric Hospital, Hanoi, VietnamNgoc Hung Nguyen - Vietnam National Geriatric Hospital, Hanoi, VietnamAnh Lan Nguyen - Vietnam National Geriatric Hospital, Hanoi, VietnamYen Hai Luong - Vietnam National Geriatric Hospital, Hanoi, VietnamBien Huu Nguyen - Hai Duong General Hospital, Hai Duong, VietnamPhong Quy Nguyen - Vietnam National Geriatric Hospital, Hanoi, VietnamLaura N. Gitlin - Drexel UniversityTrung Anh Nguyen - Vietnam National Geriatric Hospital, Hanoi, VietnamThang Pham - Vietnam National Geriatric Hospital, Hanoi, VietnamLadson Hinton - University of California, Davis
- Publication Details
- The American journal of geriatric psychiatry, v 33(5), pp P535-P545
- Publisher
- Elsevier
- Number of pages
- 11
- Grant note
- National Institute on Aging (NIA): R01AG064688 National Center for Advancing Translational Sciences (NCATS): UL1 TR001860
The study is supported by the National Institute on Aging (NIA) under award number R01AG064688 (Hin-ton and Nguyen MPI) and the National Center for Advancing Translational Sciences (NCATS) through grant UL1 TR001860 for use of REDCap. The content is solely the responsibility of the authors and does not neces-sarily represent the of fi cial views of the National Institutes of Health.
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Nursing and Health Professions
- Web of Science ID
- WOS:001445589600001
- Scopus ID
- 2-s2.0-85209230510
- Other Identifier
- 991021954776404721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Geriatrics & Gerontology
- Gerontology
- Psychiatry