Journal article
Test–retest of a phoria adaptation stimulus-induced functional MRI experiment
Journal of vision (Charlottesville, Va.), v 20(8), pp 1-15
14 Aug 2020
PMID: 32797193
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
This study was designed to identify the neural substrates activated during a phoria adaptation task using functional magnetic resonance imaging (MRI) in young adults with normal binocular vision and to test the repeatability of the fMRI measurements for this protocol. The phoria adaptation task consisted of a block protocol of 90 seconds of near visual crossed fixation followed by 90 seconds of far visual uncrossed fixation, repeated three times; the data were collected during two different experimental sessions. Results showed that the oculomotor vermis, cuneus, and primary visual cortex had the greatest functional activity within the regions of interest studied when stimulated by the phoria adaptation task. The oculomotor vermis functional activity had an intraclass correlation coefficient (ICC) of 0.3, whereas the bilateral cuneus and primary visual cortex had good ICC results of greater than 0.6. These results suggest that the sustained visual fixation task described within this study reliably activates the neural substrates of phoria adaptation. This protocol establishes a methodology that can be used in future longitudinal studies investigating therapeutic interventions that may modify phoria adaptation.
Metrics
Details
- Title
- Test–retest of a phoria adaptation stimulus-induced functional MRI experiment
- Creators
- Cristian Morales - New Jersey Institute of TechnologySuril Gohel - Rutgers, The State University of New JerseyMitchell Scheiman - Salus UniversityXiaobo Li - New Jersey Institute of TechnologyElio M. Santos - New Jersey Institute of TechnologyAyushi Sangoi - New Jersey Institute of TechnologyTara L Alvarez - New Jersey Institute of Technology
- Publication Details
- Journal of vision (Charlottesville, Va.), v 20(8), pp 1-15
- Publisher
- The Association for Research in Vision and Ophthalmology
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Pennsylvania College of Optometry (PCO)
- Web of Science ID
- WOS:000573694500009
- Scopus ID
- 2-s2.0-85089534293
- Other Identifier
- 991021900197104721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Ophthalmology