Journal article
The 2005 Benjamin Franklin medal in life sciences awarded to Elizabeth Blackburn
Journal of the Franklin Institute, v 343(3), pp 257-262
2006
Abstract
The Franklin Institute awarded the 2005 Franklin medal in life sciences to Dr. Elizabeth Blackburn for her pioneering work on understanding how the cell preserves the ends of chromosomes, telomeres, while replicating its DNA. Dr. Blackburn identified the sequence of telomere DNA, and found very simple repeat sequences that are interchangeable among many eukaryotic organisms. Subsequently, she discovered telomerase, the enzyme that ensures telomere maintenance, and demonstrated that telomerase has both RNA and protein components, with the RNA serving as the template for the reverse transcriptase. The dynamic nature of telomerase is linked to the replicative potential of the cell. Dr. Blackburn's work on telomeres has given new insights into aging and disease, including cancer.
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Details
- Title
- The 2005 Benjamin Franklin medal in life sciences awarded to Elizabeth Blackburn
- Creators
- Jane Azizkhan-Clifford - Drexel University
- Publication Details
- Journal of the Franklin Institute, v 343(3), pp 257-262
- Publisher
- Elsevier
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Web of Science ID
- WOS:000240413900007
- Scopus ID
- 2-s2.0-33746049368
- Other Identifier
- 991019168858204721
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Web of Science research areas
- Automation & Control Systems
- Engineering, Electrical & Electronic
- Engineering, Multidisciplinary
- Mathematics, Interdisciplinary Applications