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The ABCs of Immunosuppression: A Primer for Primary Care Physicians
Journal article   Peer reviewed

The ABCs of Immunosuppression: A Primer for Primary Care Physicians

Gregory Malat and Christine Culkin
The Medical clinics of North America, v 100(3), pp 505-518
May 2016
PMID: 27095642

Abstract

Graft Rejection - drug therapy Graft Rejection - immunology Humans Immunosuppression - methods Immunosuppressive Agents - adverse effects Immunosuppressive Agents - therapeutic use Kidney Transplantation Liver Transplantation Primary Health Care
Immunosuppression use for prevention of allograft recognition/rejection has evolved to reflect an expanded understanding of the immune system, as well as a fine tuning of the goals of therapy. Immunosuppression in organ transplantation represents a balance between the desire to improve the health status of an individual affected by chronic conditions versus not imposing an unintended immunodeficiency leading to iatrogenic morbidity/mortality. This article discusses the selection and general dosing of immunosuppression in organ allograft recipients to allow providers to be comfortable in monitoring immunosuppressive therapy long term and the associated, expected posttransplant complications in allograft recipients.

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Web of Science research areas
Medicine, General & Internal
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