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Journal article
The Dubai Definition and Diagnostic Criteria of Laryngopharyngeal Reflux: The IFOS Consensus
The Laryngoscope
06 Nov 2023
PMID: 37929860
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Objective The objective of this work was to gather an international consensus group to propose a global definition and diagnostic approach of laryngopharyngeal reflux (LPR) to guide primary care and specialist physicians in the management of LPR. Methods Forty‐eight international experts (otolaryngologists, gastroenterologists, surgeons, and physiologists) were included in a modified Delphi process to revise 48 statements about definition, clinical presentation, and diagnostic approaches to LPR. Three voting rounds determined a consensus statement to be acceptable when 80% of experts agreed with a rating of at least 8/10. Votes were anonymous and the analyses of voting rounds were performed by an independent statistician. Results After the third round, 79.2% of statements ( N = 38/48) were approved. LPR was defined as a disease of the upper aerodigestive tract resulting from the direct and/or indirect effects of gastroduodenal content reflux, inducing morphological and/or neurological changes in the upper aerodigestive tract. LPR is associated with recognized non‐specific laryngeal and extra‐laryngeal symptoms and signs that can be evaluated with validated patient‐reported outcome questionnaires and clinical instruments. The hypopharyngeal–esophageal multichannel intraluminal impedance–pH testing can suggest the diagnosis of LPR when there is >1 acid, weakly acid or nonacid hypopharyngeal reflux event in 24 h. Conclusion A global consensus definition for LPR is presented to improve detection and diagnosis of the disease for otolaryngologists, pulmonologists, gastroenterologists, surgeons, and primary care practitioners. The approved statements are offered to improve collaborative research by adopting common and validated diagnostic approaches to LPR. Level of Evidence 5 Laryngoscope , 2023
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Details
- Title
- The Dubai Definition and Diagnostic Criteria of Laryngopharyngeal Reflux: The IFOS Consensus
- Creators
- Jerome R. Lechien - Centre Hospitalier Universitaire de Saint-PierreMichael F. Vaezi - Vanderbilt University Medical CenterWalter W. Chan - Brigham and Women's HospitalJacqueline E. Allen - University of AucklandPetros D. Karkos - Interbalkan Medical CenterSven Saussez - Centre Hospitalier Universitaire de Saint-PierreKenneth W. Altman - Geisinger Medical CenterMilan R. Amin - New York UniversityTareck Ayad - Montreal General HospitalMaria R. Barillari - University of Campania "Luigi Vanvitelli"Peter C. Belafsky - University of California Davis Medical CenterJoel H. Blumin - Medical College of WisconsinNikki Johnston - Medical College of WisconsinFrancois Bobin - Centre Hospitalier Universitaire de PoitiersMatthew Broadhurst - Queensland Voice Centre Brisbane AustraliaFabio P. Ceccon - Hospital Israelita Albert EinsteinChristian Calvo-Henriquez - Department of Otorhinolaryngology and Head and Neck Surgery Hospital Complex of Santiago de Compostela Santiago de Compostela SpainYoung‐Gyu Eun - Kyung Hee University Medical CenterCarlos M. Chiesa-Estomba - Department of Otorhinolaryngology‐Head and Neck Surgery Hospital Universitario Donostia San Sebastian SpainLise Crevier-Buchman - Department of Otolaryngology‐Head and Neck Surgery Foch Hospital, Paris Saclay University, Research Committee of Young‐Otolaryngologists of the International Federations of Oto‐Rhino‐Laryngological Societies (YO‐IFOS) Paris FranceJohn O. Clarke - Stanford UniversityGiovanni Dapri - Humanitas GavazzeniClaudia A. Eckley - Fleury S.A. (Brazil)Camille Finck - Centre Hospitalier Universitaire de LiègeP. Marco Fisichella - AbbVie (United States)Abdul‐Latif Hamdan - American University of Beirut Medical CenterStephane Hans - Université Paris-SaclayKathy Huet - University of MonsRui Imamura - Universidade de São PauloBlair A. Jobe - Drexel UniversityToshitaka Hoppo - Drexel UniversityLance P. Maron - Netcare Park Lane Hospital Johannesburg South AfricaVinciane Muls - Centre Hospitalier Universitaire de Saint-PierreAshli K. O'Rourke - Medical University of South CarolinaPaulo S. Perazzo - Universidade Federal de São PauloGregory Postma - Augusta UniversityVyas M.N. Prasad - ENT Centre and Singapore Medical Specialist Centre Singapore SingaporeMarc Remacle - Centre Hospitalier de LuxembourgGeraldo D. Sant'Anna - Universidade Federal de Ciências da Saúde de Porto AlegreRobert T. Sataloff - Drexel UniversityEdoardo V. Savarino - University of PaduaAntonio Schindler - Luigi Sacco HospitalNora Siupsinskiene - Lithuanian University of Health SciencesPing‐Huei Tseng - National Taiwan University HospitalCraig H. Zalvan - New York Medical CollegeKarol Zelenik - University Hospital OstravaBernard Fraysse - IFOS Board Paris FranceJonathan M. Bock - Medical College of WisconsinLee M. Akst - Johns Hopkins HospitalThomas L. Carroll - Brigham and Women's Hospital
- Publication Details
- The Laryngoscope
- Publisher
- Wiley
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine
- Web of Science ID
- WOS:001106445500001
- Scopus ID
- 2-s2.0-85168811976
- Other Identifier
- 991021811629204721
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Medicine, Research & Experimental
- Otorhinolaryngology