Journal article
The Effect of Medialization Procedures on Laryngopharyngeal Reflux in Patients With Glottic Insufficiency: A Preliminary Study
Journal of voice
10 Mar 2025
PMID: 40069021
Abstract
To evaluate whether medialization procedures performed for management of glottic insufficiency also reduce patients’ concurrent laryngopharyngeal reflux (LPR) signs.
Retrospective chart review.
A retrospective chart review was conducted of patients who visited the office of the senior author, received a diagnosis of glottic insufficiency and LPR, and were offered medialization procedures. Patients were categorized into two groups: those who received medialization surgery (n = 39) and those who did not (n = 40). Reflux finding scores (RFS) collected pretreatment and post treatment were compared between groups. 24-hour pH-impedance results also were evaluated pretreatment and post treatment when available.
No significant changes were found in RFS between preintervention and postintervention within either the medialization group or the non-medialization group. Between-group comparisons showed no significant differences in RFS pre-and postintervention for each of the subcategories. Patients in the medialization group showed improvement in 24-hour pH-impedance testing with decreased total reflux events (mean reflux events pre = 59; mean reflux events post = 39) as well as total upright reflux events (mean reflux events pre = 47; mean reflux events post = 16) at the proximal sensor. However, these improvements were not statistically significant (P = 0.12, P = 0.17, respectively).
Medialization procedures in patients with glottic insufficiency may not improve the laryngeal effects of LPR. Further research with more subjects is encouraged to determine whether treating glottic insufficiency may also improve LPR symptoms.
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Details
- Title
- The Effect of Medialization Procedures on Laryngopharyngeal Reflux in Patients With Glottic Insufficiency: A Preliminary Study
- Creators
- Sriprachodaya Gaddam - Drexel University, Otolaryngology (and Head and Neck Surgery)Trevor DeSilva - Drexel University, Otolaryngology (and Head and Neck Surgery)Zachary Funk - Drexel UniversityAdam Gardi - Drexel UniversityKatherine Mullen - Drexel University, Otolaryngology (and Head and Neck Surgery)Hye Rhee Chi - Philadelphia College of Osteopathic MedicineMary J. Hawkshaw - Drexel University, Otolaryngology (and Head and Neck Surgery)Omar Ramadan - Drexel University, Otolaryngology (and Head and Neck Surgery)Robert T. Sataloff - Drexel University, Otolaryngology (and Head and Neck Surgery)
- Publication Details
- Journal of voice
- Publisher
- Elsevier Inc
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- College of Medicine; Otolaryngology (and Head and Neck Surgery)
- Scopus ID
- 2-s2.0-86000539045
- Other Identifier
- 991022040298504721