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The Healing of the Thin-Walled Expanded Polytetrafluoroethylene Vascular Graft
Journal article   Peer reviewed

The Healing of the Thin-Walled Expanded Polytetrafluoroethylene Vascular Graft

Kenji Takenaka, A. Mohsen Kholoussy, Yeng Yang, Lambros Kodellas, Teruo Matsumoto and Yonghong F Yang
Vascular surgery, v 19(6), pp 383-389
Nov 1985
DOI: https://doi.org/10.1177/153857448501900601
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

The objective of this experiment was to investigate the healing of thin-walled reinforced expanded polytetrafluoroethylene (PTFE) vascular graft (thin graft) . In 12 dogs (30-35 kgm), a 4 cm segment of each common iliac artery was excised and replaced with an equal length of PTFE vascular graft, 6mm internal diameter. Standard graft was used on one side and thin graft on the other. Dogs were sacrificed at intervals up to 12 weeks. Pannus extension started at both ends after the first week. The degree of pannus extension and pannus thickness showed no difference between both grafts at each interval. It was covered by a monolayer of endothelial-like cells as seen by scanning electron microscopy. Anastomotic hyperplasia and the growth rates of endothelialization measured from the proximal anastomosis were simi lar. No significant difference was noted in the healing between the thin-walled and standard PTFE vascular grafts for up to 12 weeks.

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9 citations in Web of Science
9 citations in Scopus

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UN Sustainable Development Goals (SDGs)

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#3 Good Health and Well-Being

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Web of Science research areas
Peripheral Vascular Disease
Surgery
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