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Accepted (AM)Open Access (License Unspecified), Open
Journal article
The Impact of Early-Life Exposure to Antimicrobials on Asthma and Eczema Risk in Children
Current environmental health reports, v 6(4), pp 214-224
01 Dec 2019
PMID: 31745828
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Purpose of ReviewWe examined recent research on associations of prenatal and early-childhood exposure to the antimicrobial compounds, triclosan, and parabens, with the risk of asthma and eczema in children. We will discuss potential biological mechanisms of this association and highlight strengths and limitations of the study design and exposure assessment of current findings.Recent FindingsResults of available toxicological and epidemiologic studies indicate a potential link of triclosan and paraben exposures with asthma and eczema in children, as well as changes in microbiome diversity and immune dysfunction, which could possibly mediate an association with the health outcomes.SummaryA small number of studies suggest that triclosan and paraben exposures could be related to the risk of asthma and eczema in children. Although current findings are far from conclusive, there is emerging evidence that changes in microbiome diversity and immune function from antimicrobial exposure may mediate these relations.
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Details
- Title
- The Impact of Early-Life Exposure to Antimicrobials on Asthma and Eczema Risk in Children
- Creators
- Medina S. Jackson-Browne - University of DelawareNoelle Henderson - Brown UniversityMarisa Patti - Brown UniversityAdam Spanier - University of Maryland, BaltimoreJoseph M. Braun - Brown University
- Publication Details
- Current environmental health reports, v 6(4), pp 214-224
- Publisher
- Springer Nature
- Number of pages
- 11
- Grant note
- F32 ES029812 / NIEHS NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS) F32ES029812 / NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Environmental Health Sciences (NIEHS)
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- A.J. Drexel Autism Institute
- Web of Science ID
- WOS:000544904800002
- Scopus ID
- 2-s2.0-85077016527
- Other Identifier
- 991022005185504721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Public, Environmental & Occupational Health