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Journal article
The Philadelphia Brief Assessment of Cognition (PBAC): A Validated Screening Measure for Dementia
Clinical neuropsychologist, v 25(8), pp 1314-1330
01 Nov 2011
PMID: 22084867
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The Philadelphia Brief Assessment of the Cognition (PBAC) is a brief dementia-screening instrument. The PBAC assesses five cognitive domains: working memory/executive control; lexical retrieval/language; visuospatial/visuoconstructional operations; verbal/visual episodic memory; and behavior/social comportment. A revised version of the PBAC was administered to 198 participants including patients with Alzheimer's disease (AD) (n = 46) and four groups of patients with frontotemporal dementia (FTD) syndromes: behavioral-variant FTD (bvFTD; n = 65), semantic-variant primary progressive aphasia (PPA) (svPPA; n = 22), non-fluent/agrammatic-variant PPA (nfaPPA; n = 23), and corticobasal syndrome (CBS; n = 42), and a group of normal controls (n = 15). The total PBAC score was highly correlated with the MMSE. The criterion validity of the PBAC was assessed relative to standard neuropsychological test performance. Using standard neuropsychological test performance as a criterion, the total PBAC score accurately identified the presence and severity of dementia. Intra-class correlations between PBAC subscales and standard neuropsychological tests were highly significant. PBAC subscales demonstrated good clinical utility in distinguishing AD and FTD subtypes using receiver operating characteristic analysis and standard diagnostic performance statistics to determine optimal subscale cut scores. The PBAC is a valid tool and able to assesses differential patterns neuropsychological/behavioral impairment in a broad range of neurodegenerative conditions.
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Details
- Title
- The Philadelphia Brief Assessment of Cognition (PBAC): A Validated Screening Measure for Dementia
- Creators
- David J. Libon - Drexel UniversityKatya Rascovsky - University of PennsylvaniaRachel G. Gross - University of PennsylvaniaMatthew T. White - University of PennsylvaniaSharon X. Xie - University of PennsylvaniaMichael Dreyfuss - University of PennsylvaniaAshley Boller - University of PennsylvaniaLauren Massimo - University of PennsylvaniaPeachie Moore - University of PennsylvaniaJessica Kitain - University of PennsylvaniaH. Branch Coslett - University of PennsylvaniaAnjan Chatterjee - University of PennsylvaniaMurray Grossman - University of Pennsylvania
- Publication Details
- Clinical neuropsychologist, v 25(8), pp 1314-1330
- Publisher
- Psychology Press
- Number of pages
- 17
- Resource Type
- Journal article
- Language
- English
- Web of Science ID
- WOS:000299559900003
- Scopus ID
- 2-s2.0-84857327979
- Other Identifier
- 991021901014004721
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InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology
- Psychology
- Psychology, Clinical