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The Prevalence of Cognitive Impairment Among Adults With Incident Heart Failure: The “Reasons for Geographic and Racial Differences in Stroke” (REGARDS) Study
Journal article   Open access   Peer reviewed

The Prevalence of Cognitive Impairment Among Adults With Incident Heart Failure: The “Reasons for Geographic and Racial Differences in Stroke” (REGARDS) Study

Madeline R Sterling, Deanna Jannat-Khah, Joanna Bryan, Samprit Banerjee, Leslie A McClure, Virginia G Wadley, Frederick W Unverzagt, Emily B Levitan, Parag Goyal, Janey C Peterson, …
Journal of cardiac failure, v 25(2), pp 130-136
Feb 2019
DOI: https://doi.org/10.1016/j.cardfail.2018.12.006
PMID: 30582968
Featured in Collection :   UN Sustainable Development Goals @ Drexel
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https://doi.org/10.1016/j.cardfail.2018.12.006View
Published, Version of Record (VoR) Open

Abstract

Heart failure prevalence cohort study cognition hospitalization
•14.9% of adults with incident heart failure (HF) had cognitive impairment (CI).•Age, race, sex, education, and anticoagulation use were associated with CI.•The prevalence of CI among an age-, sex-, and race-matched cohort without HF was 13.4%.•Findings suggest that the majority of CI in HF occurs after the HF diagnosis. Cognitive impairment (CI) is estimated to be present in 25%–80% of heart failure (HF) patients, but its prevalence at diagnosis is unclear. To improve our understanding of cognition in HF, we determined the prevalence of CI among adults with incident HF in the REGARDS study. REGARDS is a longitudinal cohort study of adults ≥45 years of age recruited in the years 2003–2007. Incident HF was expert adjudicated. Cognitive function was assessed with the Six-Item Screener. The prevalence of CI among those with incident HF was compared with the prevalence of CI among an age-, sex-, and race-matched cohort without HF. The 436 participants with incident HF had a mean age of 70.3 years (SD 8.9), 47% were female, and 39% were black. Old age, black race, female sex, less education, and anticoagulation use were associated with CI. The prevalence of CI among participants with incident HF (14.9% [95% CI 11.7%–18.6%]) was similar to the non-HF matched cohort (13.4% [11.6%–15.4%]; P < .43). A total of 14.9% of the adults with incident HF had CI, suggesting that the majority of cognitive decline occurs after HF diagnosis. Increased awareness of CI among newly diagnosed patients and ways to mitigate it in the context of HF management are warranted.

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29 citations in Web of Science
30 citations in Scopus

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UN Sustainable Development Goals (SDGs)

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#3 Good Health and Well-Being

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Collaboration types
Domestic collaboration
Web of Science research areas
Cardiac & Cardiovascular Systems
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