Journal article
The Relationship Between Adult Neuropsychological Profiles and Diabetic Patients' Glycemic Control
Applied neuropsychology, v 17(1)
10 Feb 2010
PMID: 20146121
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The purpose of this study was to assess, in relation to metabolic control, the cognitive, depressive, and anxiety symptoms among 40 adult patients (age: 18-60 years) with either type 1 (n = 28) or type 2 (n = 12) diabetes mellitus (DM1, DM2). Nineteen healthy subjects matched for age, gender, and education served as the control group. For most cognitive domains, no significant performance differences were found between subjects from the diabetic groups and control subjects. However, diabetes patients demonstrated reduced information processing accuracy along with impaired visual and verbal working memory performance. In addition, psychopathology scores were significantly elevated but did not reach the clinical criteria for depression or anxiety. Overall, there were no significant differences between diabetic subgroups, and no significant correlation was found between cognitive performance, psychopathology scores, and HbA1c values for either subgroup. Thus, patients with DM1 or DM2 may show mild-to-moderate cognitive impairment as well as subtle psychopathological symptoms. While cognitive impairments may be understood in terms of diabetes-associated cognitive dysfunction, psychopathological symptoms may also result from unsuccessful coping with high task demands in everyday life activities. The outcome of the current study underscores the importance of early clinical neuropsychological standardized assessment as well as the diagnosis of cognitive and psychopathological symptoms in adult patients with diabetes.
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Details
- Title
- The Relationship Between Adult Neuropsychological Profiles and Diabetic Patients' Glycemic Control
- Creators
- Josef Zihl - Max Planck Institute of PsychiatryLudwig Schaaf - AG Stalla, Günter, Florian Holsboer (Direktor), Max Planck Institute of Psychiatry, Max Planck SocietyEric A. Zillmer - Drexel University
- Publication Details
- Applied neuropsychology, v 17(1)
- Publisher
- Taylor & Francis Group
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychological and Brain Sciences (Psychology)
- Web of Science ID
- WOS:000274432500006
- Scopus ID
- 2-s2.0-76749162431
- Other Identifier
- 991019168624104721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Clinical Neurology
- Psychology