Journal article
The Relationship between Depressive Symptoms and Obstructive Sleep Apnea in Pediatric Populations: A Meta-Analysis
Journal of clinical sleep medicine, Vol.9(11), pp.1213-1220
01 Jan 2013
PMCID: PMC3805811
PMID: 24235907
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Background: A higher incidence of depressive disorders and symptoms has been suggested among children suffering from obstructive sleep apnea (OSA). Yet, the extent to which OSA is related to increased depression is unclear.
Objectives: To evaluate (a) the relationship between depressive symptoms and OSA in pediatric populations, and (b) the efficacy of adenotonsillectomy (AT) for decreasing depressive symptoms among children with OSA.
Methods: A meta-analysis was conducted to assess the relationship between depressive symptoms and OSA, and the efficacy of AT for decreasing depressive symptoms. Studies reporting depressive symptoms of children with OSA through January 2013 were included.
Results: Eleven studies assessed depressive symptoms in both children diagnosed with OSA (n = 894) and a comparison group (n = 1,096). A medium relationship was found between depressive symptoms and OSA (Hedges' g = 0.43, 95% CI: 0.22-0.64; p = 0.0005). Addressing the second question, 9 studies (n = 379 children) examined depressive symptoms pre- and post-AT. A medium improvement in depressive symptoms was found at follow-up (Hedge's g = 0.41, 95% CI: 0.20-0.62; p = 0.001).
Conclusion: Our findings suggest that depressive symptoms are higher among children with OSA. Therefore, patients with depressive symptomatology should receive screening for sleep disordered breathing. Treatment of OSA with AT might decrease clinical symptoms of depression, reduce pharmacotherapy, improve sleep patterns, and promote better health.
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Details
- Title
- The Relationship between Depressive Symptoms and Obstructive Sleep Apnea in Pediatric Populations: A Meta-Analysis
- Creators
- Elif Yilmaz - Drexel UniversityKarim Sedky - Rowan Univ, Cooper Med Sch, Dept Psychiat, Camden, NJ 08103 USADavid S. Bennett - Drexel University
- Publication Details
- Journal of clinical sleep medicine, Vol.9(11), pp.1213-1220
- Publisher
- Amer Acad Sleep Medicine
- Number of pages
- 8
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychiatry
- Identifiers
- 991019168059104721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Clinical Neurology