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Journal article
The Relationship between Fatigue and a Clinically Accessible Measure of Switching in Individuals with Multiple Sclerosis
Archives of clinical neuropsychology, v 37(6), pp 1208-1213
04 Apr 2022
PMID: 35381600
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Abstract
Objective
We examined whether fatigue in multiple sclerosis (MS) is linked to switching processes when switching is measured by the Trail Making Test (TMT).
Method
Eighty-three participants with MS were administered a battery of standardized tests of switching, working memory, and processing speed. Ordinary least squares regression models were used to estimate the association between fatigue severity and switching above and beyond attention, working memory, and processing speed.
Results
We found a negative association between TMT performance and fatigue severity score. When measures of processing speed and working memory were included in the model, the switching measure continued to uniquely contribute to fatigue severity.
Conclusions
There may be a unique relationship between fatigue and switching processes identifiable by clinical measures of switching. Future research should continue to investigate this relationship by using both behavioral and neural markers to test models of fatigue to eventually identify specific intervention targets.
Metrics
Details
- Title
- The Relationship between Fatigue and a Clinically Accessible Measure of Switching in Individuals with Multiple Sclerosis
- Creators
- Fareshte Erani (Corresponding Author) - Drexel UniversityJoshua McKeever - Drexel UniversityJohn D Medaglia - Drexel UniversityMaria T Schultheis - Drexel University
- Publication Details
- Archives of clinical neuropsychology, v 37(6), pp 1208-1213
- Publisher
- Oxford University Press
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Psychological and Brain Sciences (Psychology)
- Web of Science ID
- WOS:000785866000001
- Scopus ID
- 2-s2.0-85137009444
- Other Identifier
- 991019168320804721
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Psychology
- Psychology, Clinical