Files and links (1)
Published, Version of Record (VoR)CC BY V4.0, Open
Journal article
The Transport and Deposition of Nanoparticles in Respiratory System by Inhalation
Journal of nanomaterials, v 2015, pp 1-8
2015
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
The inhaled nanoparticles have attracted more and more attention, since they are more easily to enter the deep part of respiratory system. Some nanoparticles were reported to cause pulmonary inflammation. The toxicity of nanoparticles depends not only on its chemical component but also on the quantity and position of the deposition. The deposition of nanoparticles is not uniform and is influenced by airflow transport. The high deposition mainly occurs at the carinal ridges and the inside walls around the carinal ridges. Many factors could affect the transport and deposition of nanoparticles, such as particle size, flow rate, structure of airway, pulmonary function, and age. In this review, we discussed the methods and technique involved in particle transport and deposition studies. The features of particles deposition could be observed in clinic experiments and animal experiments. The mechanism of transport could be studied by numerical simulation. Numerical model and experiment study supplement each other. Some techniques such as medical imaging may support the study of nanoparticles transport and deposition. The knowledge of particles transport and deposition may be helpful both to defend the toxicity of inhaled particles and to direct inhaled drug delivery.
Metrics
Details
- Title
- The Transport and Deposition of Nanoparticles in Respiratory System by Inhalation
- Creators
- Huiting Qiao - Beihang UniversityWenyong Liu - Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, ChinaHongyu Gu - Beihang UniversityDaifa Wang - Beihang UniversityYu Wang - Beihang UniversityDong Wang - Neurobiology and Anatomy
- Publication Details
- Journal of nanomaterials, v 2015, pp 1-8
- Publisher
- Wiley
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Neurobiology and Anatomy
- Web of Science ID
- WOS:000355431300001
- Scopus ID
- 2-s2.0-84930654549
- Other Identifier
- 991019173417404721
UN Sustainable Development Goals (SDGs)
This publication has contributed to the advancement of the following goals:
InCites Highlights
Data related to this publication, from InCites Benchmarking & Analytics tool:
- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Materials Science, Multidisciplinary
- Nanoscience & Nanotechnology