Journal article
The Upcoming Epidemic of Heart Failure in South Asia
Circulation. Heart failure, v 13(10), pp e007218-e007218
01 Oct 2020
PMID: 32962410
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Currently, South Asia accounts for a quarter of the world population, yet it already claims approximate to 60% of the global burden of heart disease. Besides the epidemics of type 2 diabetes mellitus and coronary heart disease already faced by South Asian countries, recent studies suggest that South Asians may also be at an increased risk of heart failure (HF), and that it presents at earlier ages than in most other racial/ethnic groups. Although a frequently underrecognized threat, an eventual HF epidemic in the densely populated South Asian nations could have dramatic health, social and economic consequences, and urgent interventions are needed to flatten the curve of HF in South Asia. In this review, we discuss recent studies portraying these trends, and describe the mechanisms that may explain an increased risk of premature HF in South Asians compared with other groups, with a special focus on highly relevant features in South Asian populations including premature coronary heart disease, early type 2 diabetes mellitus, ubiquitous abdominal obesity, exposure to the world's highest levels of air pollution, highly prevalent pretransition forms of HF such as rheumatic heart disease, and underdevelopment of healthcare systems. Other rising lifestyle-related risk factors such as use of tobacco products, hypertension, and general obesity are also discussed. We evaluate the prognosis of HF in South Asian countries and the implications of an anticipated HF epidemic. Finally, we discuss proposed interventions aimed at curbing these adverse trends, management approaches that can improve the prognosis of prevalent HF in South Asian countries, and research gaps in this important field.
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Details
- Title
- The Upcoming Epidemic of Heart Failure in South Asia
- Creators
- Pablo Martinez-Amezcua - Johns Hopkins Bloomberg School of Public Health (P.M.-A., W.H.), Johns Hopkins University, Baltimore, MD.Waqas Haque - Johns Hopkins UniversityRohan Khera - Yale UniversityAlka M. Kanaya - University of California, San FranciscoNaveed Sattar - University of GlasgowCarolyn S. P. Lam - National University of SingaporeSivadasanpillai Harikrishnan - National Center of Research and Excellence in Heart Failure, ICMR (S.H.).Sanjiv J. Shah - Bluhm Cardiovascular Institute and Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (S.J.S.).Namratha R. Kandula - Northwestern UniversityPowell O. Jose - Sutter Medical CenterK. M. Venkat Narayan - Emory UniversityCharles Agyemang - University of AmsterdamAnoop Misra - Center for Excellence in EducationAnne K. Jenum - General Practice Research Unit (AFE), Department of General Practice, University of Oslo, Institute of Health and Society, Norway (A.K.J.).Usama Bilal - Supreme Council Of HealthKhurram Nasir - Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University, Baltimore, MD. (W.H., K.N., M.C.-A.).Miguel Cainzos-Achirica - Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University, Baltimore, MD. (W.H., K.N., M.C.-A.).
- Publication Details
- Circulation. Heart failure, v 13(10), pp e007218-e007218
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 15
- Grant note
- RE/18/6/34217 / British Heart Foundation Research Excellence Award
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000582390700011
- Scopus ID
- 2-s2.0-85094221039
- Other Identifier
- 991019167697404721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems