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The application of biofilm science to the study and control of chronic bacterial infections
Journal article   Peer reviewed

The application of biofilm science to the study and control of chronic bacterial infections

William Costerton, Richard Veeh, Mark Shirtliff, Mark Pasmore, Christopher Post and Garth Ehrlich
The Journal of clinical investigation, v 112(10), pp 1466-1477
15 Nov 2003
PMID: 14617746
url
https://doi.org/10.1172/JCI200320365View
Published, Version of Record (VoR) Restricted

Abstract

Series
Unequivocal direct observations have established that the bacteria that cause device-related and other chronic infections grow in matrix-enclosed biofilms. The diagnostic and therapeutic strategies that have served us so well in the partial eradication of acute epidemic bacterial diseases have not yielded accurate data or favorable outcomes when applied to these biofilm diseases. We discuss the potential benefits of the application of the new methods and concepts developed by biofilm science and engineering to the clinical management of infectious diseases.

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666 citations in Scopus

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Collaboration types
Domestic collaboration
Web of Science research areas
Medicine, Research & Experimental
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