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The biomechanical effects of kyphoplasty on treated and adjacent nontreated vertebral bodies
Journal article

The biomechanical effects of kyphoplasty on treated and adjacent nontreated vertebral bodies

Marta L Villarraga, Anthony J Bellezza, Timothy P Harrigan, Peter A Cripton, Steven M Kurtz and Avram A Edidin
Journal of spinal disorders & techniques, v 18(1), pp 84-91
Feb 2005
DOI: https://doi.org/10.1097/01.bsd.0000138694.56012.ce
PMID: 15687858
Featured in Collection :   UN Sustainable Development Goals @ Drexel

Abstract

Biomechanical Phenomena Bone Cements - standards Cementation - methods Cementation - standards Intervertebral Disc - anatomy & histology Intervertebral Disc - surgery Kyphosis - pathology Kyphosis - surgery Lumbar Vertebrae - anatomy & histology Lumbar Vertebrae - physiology Lumbar Vertebrae - surgery Models, Anatomic Retrospective Studies Stress, Mechanical Thoracic Vertebrae - anatomy & histology Thoracic Vertebrae - physiology Thoracic Vertebrae - surgery
It remains unclear whether adjacent vertebral body fractures are related to the natural progression of osteoporosis or if adjacent fractures are a consequence of augmentation with bone cement. Experimental or computational studies have not completely addressed the biomechanical effects of kyphoplasty on adjacent levels immediately following augmentation. This study presents a validated two-functional spinal unit (FSU) T12-L2 finite element model with a simulated kyphoplasty augmentation in L1 to predict stresses and strains within the bone cement and bone of the treated and adjacent nontreated vertebral bodies. The findings from this multiple-FSU study and a recent retrospective clinical study suggest that changes in stresses and strains in levels adjacent to a kyphoplasty-treated level are minimal. Furthermore, the stress and strain levels found in the treated levels are less than injury tolerance limits of cancellous and cortical bone. Therefore, subsequent adjacent level fractures may be related to the underlying etiology (weakening of the bone) rather than the surgical intervention.

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92 citations in Web of Science
108 citations in Scopus

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Collaboration types
Industry collaboration
Domestic collaboration
International collaboration
Web of Science research areas
Clinical Neurology
Orthopedics
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