Journal article
The effect of nucleus implant parameters on the compressive mechanics of the lumbar intervertebral disc: a finite element study
Journal of biomedical materials research. Part B, Applied biomaterials, v 90(2), pp 596-607
Aug 2009
PMID: 19180527
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
A simplified finite element model of the human lumbar intervertebral disc was utilized for understanding nucleus pulposus implant mechanics. The model was used to assess the effect of nucleus implant parameter variations on the resulting compressive biomechanics of the lumbar anterior column unit. The effects of nucleus implant material (modulus and Poisson's ratio) and geometrical (height and diameter) parameters on the mechanical behavior of the disc were investigated. The model predicted that variations in implant modulus contribute less to the compressive disc mechanics compared to the implant geometrical parameters, for the ranges examined. It was concluded that some threshold exists for the nucleus implant modulus, below which little variations in load-displacement behavior were shown. Compressive biomechanics were highly affected by implant volume (under-filling the nucleus cavity, line-to-line fit, or over-filling the nucleus cavity) with a greater restoration of compressive mechanics observed with the over-filled implant design. This work indicated the effect of nucleus implant parameter variations on the compressive mechanics of the human lumbar intervertebral disc and importance of the "fit and fill" effect of the nuclear cavity in the restoration of the human intervertebral disc mechanics in compression. These findings may have clinical significance for nucleus implant design.
Metrics
Details
- Title
- The effect of nucleus implant parameters on the compressive mechanics of the lumbar intervertebral disc: a finite element study
- Creators
- Abhijeet Joshi - Department of Materials Science and Engineering, Drexel University, Philadelphia, Pennsylvania, USAChristopher J MasseyAndrew KardunaEdward VresilovicMichele Marcolongo
- Publication Details
- Journal of biomedical materials research. Part B, Applied biomaterials, v 90(2), pp 596-607
- Publisher
- Wiley; United States
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Materials Science and Engineering
- Web of Science ID
- WOS:000268114200014
- Scopus ID
- 2-s2.0-67749142427
- Other Identifier
- 991014877802804721
UN Sustainable Development Goals (SDGs)
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Source: SDGs in the Output
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- Collaboration types
- Domestic collaboration
- Web of Science research areas
- Engineering, Biomedical
- Materials Science, Biomaterials