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Journal article
The impact of lifecourse socioeconomic position on cardiovascular disease events in African Americans: the Jackson Heart Study
Journal of the American Heart Association, v 4(6), pp e001553-e001553
27 May 2015
PMID: 26019130
Featured in Collection : UN Sustainable Development Goals @ Drexel
Abstract
Few studies have examined the impact of lifecourse socioeconomic position (SEP) on cardiovascular disease (CVD) risk among African Americans.
We used data from the Jackson Heart Study (JHS) to examine the associations of multiple measures of lifecourse SEP with CVD events in a large cohort of African Americans. During a median of 7.2-year follow-up, 362 new or recurrent CVD events occurred in a sample of 5301 participants aged 21 to 94. Childhood SEP was assessed by using mother's education, parental home ownership, and childhood amenities. Adult SEP was assessed by using education, income, wealth, and public assistance. Adult SEP was more consistently associated with CVD risk in women than in men: age-adjusted hazard ratios for low versus high income (95% CIs), 2.46 (1.19 to 5.09) in women and 1.50 (0.87 to 2.58) in men, P for interaction=0.1244, and hazard ratio for low versus high wealth, 2.14 (1.39 to 3.29) in women and 1.06 (0.62 to 1.81) in men, P for interaction=0.0224. After simultaneous adjustment for all adult SEP measures, wealth remained a significant predictor of CVD events in women (HR=1.73 [1.04, 2.85] for low versus high). Education and public assistance were less consistently associated with CVD. Adult SEP was a stronger predictor of CVD events in younger than in older participants (HR for high versus low summary adult SEP score 3.28 [1.43, 7.53] for participants ≤50 years, and 1.90 (1.36 to 2.66) for participants >50 years, P for interaction 0.0846). Childhood SEP was not associated with CVD risk in women or men.
Adult SEP is an important predictor of CVD events in African American women and in younger African Americans. Childhood SEP was not associated with CVD events in this population.
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Details
- Title
- The impact of lifecourse socioeconomic position on cardiovascular disease events in African Americans: the Jackson Heart Study
- Creators
- Samson Y Gebreab - National Human Genome Research InstituteAna V Diez Roux - Drexel UniversityAllison B Brenner - Department of Epidemiology, School of Public Health, University of Michigan, Jackson, MS (A.B.B.).DeMarc A Hickson - University of Mississippi Medical CenterMario Sims - University of Mississippi Medical CenterMalavika Subramanyam - Indian Institute of Technology GandhinagarMichael E Griswold - University of Mississippi Medical CenterSharon B Wyatt - University of Mississippi Medical CenterSherman A James - Emory University
- Publication Details
- Journal of the American Heart Association, v 4(6), pp e001553-e001553
- Grant note
- HHSN268201300049C / PHS HHS HHSN268201300046C / PHS HHS 2P60MD002249 / NIMHD NIH HHS HHSN268201300050C / PHS HHS HHSN268201300048C / PHS HHS P60 MD002249 / NIMHD NIH HHS HHSN268201300047C / PHS HHS
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- Urban Health Collaborative
- Web of Science ID
- WOS:000357025100008
- Scopus ID
- 2-s2.0-85018231852
- Other Identifier
- 991019168283604721
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- Collaboration types
- Domestic collaboration
- International collaboration
- Web of Science research areas
- Cardiac & Cardiovascular Systems