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The low affinity binding site for the cocaine analog, WIN 35,428 is an artifact of freezing caudate tissue
Journal article   Peer reviewed

The low affinity binding site for the cocaine analog, WIN 35,428 is an artifact of freezing caudate tissue

A L Kirifides, J A Harvey and V Aloyo
Life sciences (1973), v 50(17), pp L139-L142
01 Jan 1992
PMID: 1569826

Abstract

analogs artifacts binding brain caudate nucleus characterization cocaine rabbits
Binding of the cocaine analog ( super(3)H) WIN 35,428 was investigated in rat and rabbit caudate. In membranes prepared from fresh tissue, ( super(3)H) WIN 35,428 binding was characterized by a single high affinity site with a K sub(d) of 2.5 nM for the rabbit and 5.3 nM for the rat.

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Web of Science research areas
Medicine, Research & Experimental
Pharmacology & Pharmacy
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