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The matrix in focus: new directions in extracellular matrix research from the 2021 ASMB hybrid meeting
Journal article   Open access   Peer reviewed

The matrix in focus: new directions in extracellular matrix research from the 2021 ASMB hybrid meeting

Bryan A. Nerger, Tia M. Jones, Keron W. J. Rose, Anna Barque, Justin S. Weinbaum, Ryan J. Petrie, Joan Chang, Davy Vanhoutte, Kendra LaDuca, Dirk Hubmacher, …
Biology open, v 11(1)
01 Jan 2022
PMID: 34994383
url
https://doi.org/10.1242/bio.059156View
Published, Version of Record (VoR)CC BY V4.0 Open

Abstract

Biology Life Sciences & Biomedicine Life Sciences & Biomedicine - Other Topics Science & Technology
The extracellular matrix (ECM) is a complex assembly of macromolecules that provides both architectural support and molecular signals to cells and modulate their behaviors. Originally considered a passive mechanical structure, decades of research have since demonstrated how the ECM dynamically regulates a diverse set of cellular processes in development, homeostasis, and disease progression. In September 2021, the American Society for Matrix Biology (ASMB) organized a hybrid scientific meeting, integrating in-person and virtual formats, to discuss the latest developments in ECM research. Here, we highlight exciting scientific advances that emerged from the meeting including (1) the use of model systems for fundamental and translation ECM research, (2) ECM-targeting approaches as therapeutic modalities, (3) cellECM interactions, and (4) the ECM as a critical component of tissue engineering strategies. In addition, we discuss how the ASMB incorporated mentoring, career development, and diversity, equity, and inclusion initiatives in both virtual and in-person events. Finally, we reflect on the hybrid scientific conference format and how it will help the ASMB accomplish its mission moving forward.

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Biology
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