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The maturational effects of LSD upon brain weight and behavior in the mouse
Journal article

The maturational effects of LSD upon brain weight and behavior in the mouse

Cecilie A. Goodrich, Kenneth M. Hoff and Peter C. Baker
Comparative and general pharmacology, v 5(2), pp 153-155
1974

Abstract

behavior brain LSD Lysergic acid diethylamide mouse
1. Mice exposed to LSD on day 1 or day 7 post-partum showed no altered exploratory behavior when tested by the ‘head poke’ test at 8 weeks post-partum. 2. Male mice exposed to LSD (5·0 and 50·0 μg./kg.) on day 1 post-partum showed reduced brain weight in some regions of the brain when measured at 8 weeks post-partum. Male mice exposed to LSD on day 7 and female mice exposed on day 1 or day 7 showed no such weight change.

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