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The numb chin in breast cancer
Journal article   Open access   Peer reviewed

The numb chin in breast cancer

John Horton, Eugene D. Means, T. J. Cunningham and Kenneth B. Olson
Journal of neurology, neurosurgery and psychiatry, v 36(2), pp 211-216
Apr 1973
PMID: 4708456
url
https://doi.org/10.1136/jnnp.36.2.211View
Published, Version of Record (VoR) Open

Abstract

Numbness of the chin, an uncommon neurological symptom, was observed in 15 patients with cancer. Thirteen had breast cancer. This symptom usually heralded progressive involvement of the cranial nerves or cerebrum and denoted a poor prognosis in patients with a short `tumourfree interval'. The pathogenesis is commonly related to dural involvement of the Vth cranial nerve at the base of the brain, although metastasis to the mandible might sometimes be implicated. The reason for the peculiar predilection for the mandibular branch of the trigeminal nerve to be affected by breast cancer is not known.

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