Journal article
The population of a misfolded state of cytochrome c under folding conditions
Biochemistry (Easton), Vol.52(3), p1397
22 Jan 2013
Abstract
The discovery of a (meta)stable partially unfolded state of horse heart ferricytochromec that was obtained after exposing the protein to a solution with an alkaline pH of 11.5 for 1 week is described in this article. The study data indicates a partially unfolded ferricytochrome c conformation with spectroscopic characteristics reminiscent of the recently discovered alkaline isomer [V.sub.b], which is stabilized under folding conditions by exposing the protein to a very alkaline pH for an extended period of time.
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Details
- Title
- The population of a misfolded state of cytochrome c under folding conditions
- Creators
- Jonathan B SofferEmma FradkinLeah A PandisciaReinhard Schweitzer-Stenner
- Publication Details
- Biochemistry (Easton), Vol.52(3), p1397
- Publisher
- American Chemical Society
- Resource Type
- Journal article
- Language
- English
- Academic Unit
- [Retired Faculty]
- Identifiers
- 991019196702604721